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Target
P2Y purinoceptor 11
Ligand
BDBM50131060
Substrate
n/a
Meas. Tech.
ChEBML_1526465
EC50
1000±n/a nM
Citation
 Azran, S; Danino, O; Förster, D; Kenigsberg, S; Reiser, G; Dixit, M; Singh, V; Major, DT; Fischer, B Identification of Highly Promising Antioxidants/Neuroprotectants Based on Nucleoside 5'-Phosphorothioate Scaffold. Synthesis, Activity, and Mechanisms of Action. J Med Chem 58:8427-43 (2015) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 11
Synonyms:
P2RY11 | P2Y purinoceptor 11 | P2Y11 | P2Y11_HUMAN | Purinergic receptor P2Y11
Type:
PROTEIN
Mol. Mass.:
40366.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1362532
Residue:
374
Sequence:
MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ
  
Inhibitor
Name:
BDBM50131060
Synonyms:
CHEMBL3634186
Type:
Small organic molecule
Emp. Form.:
C10H14ClN5O9P2S
Mol. Mass.:
477.712
SMILES:
Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(S)=O)[C@@H](O)[C@H]1O |r|
Structure:
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