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TargetCannabinoid receptor 1/Mu-type opioid receptor
LigandBDBM50135224
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1546048
Ki 7.4±n/a nM
Citation Schembri, LSStoddart, LABriddon, SJKellam, BCanals, MGraham, BScammells, PJ Synthesis, Biological Evaluation, and Utility of Fluorescent Ligands Targeting theľ-Opioid Receptor. J Med Chem58:9754-67 (2015) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 1/Mu-type opioid receptor
Name:Cannabinoid receptor 1/Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50135224
NameBDBM50135224
Synonyms:CHEMBL3747778
TypeSmall organic molecule
Emp. Form.C32H45N3O6
Mol. Mass.567.7162
SMILES[H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@]51C[C@H](C(=O)NCCCCCCNC(=O)OC(C)(C)C)[C@]2(OC)C=C1)ccc3O |r,wU:1.0,13.12,wD:34.38,16.19,14.42,7.7,c:41,THB:10:9:14:6.4.5,(-3.13,.26,;-2.17,.57,;-3.33,2.18,;-2.17,3.75,;-.8,2.95,;.55,3.75,;1.91,2.95,;1.91,1.38,;1.04,1.89,;3.29,.57,;4.08,-.36,;2.69,2.13,;.51,2.15,;-.8,1.38,;.55,.57,;.55,-.97,;-.8,-1.76,;-.79,-3.28,;.26,-3.89,;-2.11,-4.05,;-2.1,-5.57,;-3.41,-6.34,;-3.41,-7.86,;-4.72,-8.62,;-4.71,-10.14,;-6.03,-10.91,;-6.02,-12.43,;-7.33,-13.2,;-8.39,-12.6,;-7.33,-14.72,;-8.64,-15.49,;-8.64,-16.7,;-9.7,-14.88,;-9.69,-16.1,;-2.17,-.97,;-1.43,.37,;-2.07,1.4,;-.87,-.71,;-.87,.27,;.55,5.33,;-.8,6.12,;-2.17,5.33,;-3.22,5.94,)|
Structure
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