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Target
Suppressor of tumorigenicity 14 protein homolog
Ligand
BDBM50135272
Substrate
n/a
Meas. Tech.
ChEMBL_1544368 (CHEMBL3748444)
Ki
246±n/a nM
Citation
 Kwon, H; Kim, Y; Park, K; Choi, SA; Son, SH; Byun, Y Structure-based design, synthesis, and biological evaluation of Leu-Arg dipeptide analogs as novel hepsin inhibitors. Bioorg Med Chem Lett 26:310-4 (2016) [PubMed]  Article 
Target
Name:
Suppressor of tumorigenicity 14 protein homolog
Synonyms:
Epithin | Prss14 | ST14_MOUSE | Serine protease 14 | St14 | Suppressor of tumorigenicity 14 protein homolog
Type:
PROTEIN
Mol. Mass.:
94658.46
Organism:
Mus musculus
Description:
ChEMBL_116697
Residue:
855
Sequence:
MGSNRGRKAGGGSQDFGAGLKYNSRLENMNGFEEGVEFLPANNAKKVEKRGPRRWVVLVAVLFSFLLLSLMAGLLVWHFHYRNVRVQKVFNGHLRITNEIFLDAYENSTSTEFISLASQVKEALKLLYNEVPVLGPYHKKSAVTAFSEGSVIAYYWSEFSIPPHLAEEVDRAMAVERVVTLPPRARALKSFVLTSVVAFPIDPRMLQRTQDNSCSFALHAHGAAVTRFTTPGFPNSPYPAHARCQWVLRGDADSVLSLTFRSFDVAPCDEHGSDLVTVYDSLSPMEPHAVVRLCGTFSPSYNLTFLSSQNVFLVTLITNTDRRHPGFEATFFQLPKMSSCGGFLSDTQGTFSSPYYPGHYPPNINCTWNIKVPNNRNVKVRFKLFYLVDPNVPVGSCTKDYVEINGEKYCGERSQFVVSSNSSKITVHFHSDHSYTDTGFLAEYLSYDSNDPCPGMFMCKTGRCIRKELRCDGWADCPDYSDERYCRCNATHQFTCKNQFCKPLFWVCDSVNDCGDGSDEEGCSCPAGSFKCSNGKCLPQSQKCNGKDNCGDGSDEASCDSVNVVSCTKYTYRCQNGLCLSKGNPECDGKTDCSDGSDEKNCDCGLRSFTKQARVVGGTNADEGEWPWQVSLHALGQGHLCGASLISPDWLVSAAHCFQDDKNFKYSDYTMWTAFLGLLDQSKRSASGVQELKLKRIITHPSFNDFTFDYDIALLELEKSVEYSTVVRPICLPDATHVFPAGKAIWVTGWGHTKEGGTGALILQKGEIRVINQTTCEDLMPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWGEGCAQRNKPGVYTRLPVVRDWIKEHTGV
  
Inhibitor
Name:
BDBM50135272
Synonyms:
CHEMBL3747618
Type:
Small organic molecule
Emp. Form.:
C17H28N6O3S
Mol. Mass.:
396.508
SMILES:
CC(C)C[C@H](NC(C)=O)C(=O)N[C@H](CCCNC(N)=N)C(=O)c1nccs1 |r|
Structure:
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