Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetMelatonin receptor
LigandBDBM50139842
Substrate/Competitorn/a
Meas. Tech.ChEBML_1553992
Ki 0.200000±n/a nM
Citation Couhert, ADelagrange, PCaignard, DHChartier, ASuzenet, FGuillaumet, G Synthesis of 2-arylfuro[3,2-b]pyridines: Effect of the C2-aryl group on melatoninergic activity. Eur J Med Chem109:268-75 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50139842
NameBDBM50139842
Synonyms:CHEMBL3765401
TypeSmall organic molecule
Emp. Form.C12H13IN2O3
Mol. Mass.360.1477
SMILESCOc1ccc2oc(I)c(CCNC(C)=O)c2n1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a