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TargetAdenosylhomocysteinase 2
LigandBDBM50140074
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1547422
IC50 2.7±n/a nM
Citation Liu, CChen, QSchneller, SW Enantiomeric 3-deaza-1',6'-isoneplanocin and its 3-bromo analogue: Synthesis by the Ullmann reaction and their antiviral properties. Bioorg Med Chem Lett26:928-30 (2016) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Adenosylhomocysteinase 2
Name:Adenosylhomocysteinase 2
Synonyms:AHCYL1 | Adenosylhomocysteinase 2 | AdoHcyase 2 | DC-expressed AHCY-like molecule | DCAL | IP(3)Rs binding protein released with IP(3) | IRBIT
Type:PROTEIN
Mol. Mass.:58952.83
Organism:Homo sapiens
Description:ChEMBL_116703
Residue:530
Sequence:
MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
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  Blast E-value cutoff:
BDBM50140074
NameBDBM50140074
Synonyms:CHEMBL2059155
TypeSmall organic molecule
Emp. Form.C12H13BrN4O3
Mol. Mass.341.161
SMILESNc1ncc(Br)c2n(cnc12)[C@@H]1C=C(CO)[C@@H](O)[C@H]1O |r,t:14|
Structure
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n/a