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Target
Melatonin receptor type 1A
Ligand
BDBM50144310
Substrate
n/a
Meas. Tech.
ChEMBL_1551497 (CHEMBL3762918)
EC50
9.5±n/a nM
Citation
 Landagaray, E; Ettaoussi, M; Duroux, R; Boutin, JA; Caignard, DH; Delagrange, P; Melnyk, P; Berthelot, P; Yous, S Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives. Eur J Med Chem 109:360-70 (2016) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50144310
Synonyms:
CHEMBL3759084
Type:
Small organic molecule
Emp. Form.:
C16H14FNO3
Mol. Mass.:
287.2857
SMILES:
COc1ccc2ccc3oc(CNC(=O)CF)cc3c2c1
Structure:
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