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Target
Nuclear receptor subfamily 1 group I member 3
Ligand
BDBM50146183
Substrate
n/a
Meas. Tech.
ChEMBL_1555044 (CHEMBL3767622)
IC50
35±n/a nM
Citation
 Lin, W; Yang, L; Chai, SC; Lu, Y; Chen, T Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor. Eur J Med Chem 108:505-28 (2016) [PubMed]  Article 
Target
Name:
Nuclear receptor subfamily 1 group I member 3
Synonyms:
CAR | NR1I3 | NR1I3_HUMAN
Type:
PROTEIN
Mol. Mass.:
39953.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1434936
Residue:
352
Sequence:
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
  
Inhibitor
Name:
BDBM50146183
Synonyms:
CHEMBL3765692
Type:
Small organic molecule
Emp. Form.:
C24H30N2O4
Mol. Mass.:
410.506
SMILES:
CCC(C)OCC(=O)N1c2ccccc2CCc2ccc(NC(=O)OC(C)C)cc12
Structure:
Search PDB for entries with ligand similarity: