Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50156814
Substrate
n/a
Meas. Tech.
ChEMBL_1571936 (CHEMBL3796328)
Ki
>10000±n/a nM
Citation
 Witt, JO; McCollum, AL; Hurtado, MA; Huseman, ED; Jeffries, DE; Temple, KJ; Plumley, HC; Blobaum, AL; Lindsley, CW; Hopkins, CR Synthesis and characterization of a series of chiral alkoxymethyl morpholine analogs as dopamine receptor 4 (D4R) antagonists. Bioorg Med Chem Lett 26:2481-8 (2016) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50156814
Synonyms:
CHEMBL3792731
Type:
Small organic molecule
Emp. Form.:
C18H20ClNOS
Mol. Mass.:
333.876
SMILES:
Clc1ccc(CN2CCO[C@H](CSc3ccccc3)C2)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: