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TargetAdrenergic beta-2 receptor (beta2)
LigandBDBM50167072
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1573519
Ki 0.034000±n/a nM
Citation Weichert, DStanek, MHübner, HGmeiner, P Structure-guided development of dualß2 adrenergic/dopamine D2 receptor agonists. Bioorg Med Chem24:2641-53 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adrenergic beta-2 receptor (beta2)
Name:Adrenergic beta-2 receptor (beta2)
Synonyms:ADRB2 | ADRB2R | ADRB2R, B2AR | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:n/a
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50167072
NameBDBM50167072
Synonyms:CHEMBL3799125
TypeSmall organic molecule
Emp. Form.C24H26N2O4
Mol. Mass.406.4742
SMILESCOc1ccccc1OCCNC[C@H](O)COc1cccc2[nH]c3ccccc3c12 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a