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Target
Aminopeptidase B
Ligand
BDBM23971
Substrate
n/a
Meas. Tech.
ChEMBL_1580949 (CHEMBL3812617)
IC50
160000±n/a nM
Citation
 Gunaydin, H; Bartberger, MD Stacking with No Planarity? ACS Med Chem Lett 7:341-4 (2016) [PubMed]  Article 
Target
Name:
Aminopeptidase B
Synonyms:
AMPB_HUMAN | APB | Aminopeptidase | Ap-B | Arginine aminopeptidase | Arginyl aminopeptidase | RNPEP
Type:
PROTEIN
Mol. Mass.:
72586.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_36048
Residue:
650
Sequence:
MASGEHSPGSGAARRPLHSAQAVDVASASNFRAFELLHLHLDLRAEFGPPGPGAGSRGLSGTAVLDLRCLEPEGAAELRLDSHPCLEVTAAALRRERPGSEEPPAEPVSFYTQPFSHYGQALCVSFPQPCRAAERLQVLLTYRVGEGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAEPCLIDAAKEEYNGVIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKETFASTASQLHSNVVNYVQQIVAPKGS
  
Inhibitor
Name:
BDBM23971
Synonyms:
(2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido]-4-methylpentanoic acid | Bestatin | CHEMBL29292 | Ubenimex
Type:
Small organic molecule
Emp. Form.:
C16H24N2O4
Mol. Mass.:
308.3728
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Structure:
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