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Target
Delta-type opioid receptor
Ligand
BDBM50174071
Substrate
n/a
Meas. Tech.
ChEMBL_1581396 (CHEMBL3812003)
Ki
>10000±n/a nM
Citation
 Shen, Q; Qian, Y; Huang, X; Xu, X; Li, W; Liu, J; Fu, W Discovery of Potent and Selective Agonists ofd Opioid Receptor by Revisiting the"Message-Address" Concept. ACS Med Chem Lett 7:391-6 (2016) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50174071
Synonyms:
CHEMBL3808800
Type:
Small organic molecule
Emp. Form.:
C26H26F3NO2
Mol. Mass.:
441.4853
SMILES:
CN(C)C[C@H]1CCc2cc(ccc2[C@]1(O)c1cccc(O)c1)-c1ccc(cc1)C(F)(F)F |r|
Structure:
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