Reaction Details Report a problem with these data
Target
Potassium voltage-gated channel subfamily A member 3
Ligand
BDBM50176999
Substrate
n/a
Meas. Tech.
ChEBML_1582264
EC50
1000±n/a nM
Citation
 Baell, JB Feeling Nature's PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS). J Nat Prod 79:616-28 (2016) [PubMed]  Article 
Target
Name:
Potassium voltage-gated channel subfamily A member 3
Synonyms:
KCNA3_MOUSE | Kcna3 | MK3 | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel subunit Kv1.3
Type:
PROTEIN
Mol. Mass.:
58553.58
Organism:
Mus musculus
Description:
ChEMBL_1513943
Residue:
528
Sequence:
MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGGGGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
  
Inhibitor
Name:
BDBM50176999
Synonyms:
CHEMBL3814333
Type:
Small organic molecule
Emp. Form.:
C20H20O5
Mol. Mass.:
340.3698
SMILES:
COc1c(C(C)=O)c(O)c(OCCCc2ccccc2)c2occc12
Structure:
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