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Target
Nuclear receptor subfamily 1 group I member 3
Ligand
BDBM50030476
Substrate
n/a
Meas. Tech.
ChEMBL_1587671 (CHEMBL3825785)
EC50
20±n/a nM
Citation
 Smutny, T; Nova, A; Drechslerová, M; Carazo, A; Hyrsova, L; Hru?ková, ZR; Kune?, J; Pour, M; ?pulák, M; Pavek, P 2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists. J Med Chem 59:4601-10 (2016) [PubMed]  Article 
Target
Name:
Nuclear receptor subfamily 1 group I member 3
Synonyms:
CAR | NR1I3 | NR1I3_HUMAN
Type:
PROTEIN
Mol. Mass.:
39953.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1434936
Residue:
352
Sequence:
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
  
Inhibitor
Name:
BDBM50030476
Synonyms:
CHEMBL458603
Type:
Small organic molecule
Emp. Form.:
C19H12Cl3N3OS
Mol. Mass.:
436.742
SMILES:
Clc1ccc(cc1)-c1nc2sccn2c1\C=N\OCc1ccc(Cl)c(Cl)c1
Structure:
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