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TargetAlpha-2B adrenergic receptor
LigandBDBM50193034
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1614153
EC50 3162±n/a nM
Citation Giusepponi, MECifani, CMicioni Di Bonaventura, MVMattioli, LHudson, ADiamanti, EDel Bello, FGiannella, MMammoli, VPaoletti, CDPiergentili, APigini, MQuaglia, W Combined Interactions with I ACS Med Chem Lett7:956-961 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-2B adrenergic receptor
Name:Alpha-2B adrenergic receptor
Synonyms:ADRA2B | ADRA2L1 | ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:Enzyme
Mol. Mass.:49579.89
Organism:Homo sapiens (Human)
Description:P18089
Residue:450
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRR
AQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSS
LNPVIYTIFNQDFRRAFRRILCRPWTQTAW
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  Blast E-value cutoff:
BDBM50193034
NameBDBM50193034
Synonyms:CHEMBL3904276
TypeSmall organic molecule
Emp. Form.C11H15N3
Mol. Mass.189.2569
SMILESCc1ccccc1NCC1=NCCN1 |t:10|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a