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Target
Alpha-galactosidase
Ligand
BDBM50375511
Substrate
n/a
Meas. Tech.
ChEMBL_1620013 (CHEMBL3862296)
Ki
2000±n/a nM
Citation
 Mena-Barragán, T; García-Moreno, MI; Nanba, E; Higaki, K; Concia, AL; Clapés, P; García Fernández, JM; Ortiz Mellet, C Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts. Eur J Med Chem 121:880-891 (2016) [PubMed]  Article 
Target
Name:
Alpha-galactosidase
Synonyms:
α-galactosidase | AGAL_COFAR | Alpha-galactosidase
Type:
Protein
Mol. Mass.:
41306.82
Organism:
Coffea arabica (Coffee beans)
Description:
n/a
Residue:
378
Sequence:
MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGYKYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTMPGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWGEEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGMTTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYGDLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQISAAVDAHDSKMYVLTPQ
  
Inhibitor
Name:
BDBM50375511
Synonyms:
CHEMBL406973
Type:
Small organic molecule
Emp. Form.:
C5H11NO3
Mol. Mass.:
133.1457
SMILES:
OC[C@@H]1NC[C@H](O)[C@H]1O
Structure:
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