Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50200987
Substrate
n/a
Meas. Tech.
ChEMBL_1622887 (CHEMBL3865239)
Ki
3.0±n/a nM
Citation
 Rosse, G Quinazoline Carboxamides as Selective Antagonists of Adenosine 2A Receptor. ACS Med Chem Lett 7:1014-1015 (2016) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50200987
Synonyms:
CHEMBL3920917 | US10138212, Example 23
Type:
Small organic molecule
Emp. Form.:
C17H17N5O3
Mol. Mass.:
339.3486
SMILES:
COc1cccnc1CNC(=O)c1nc(N)nc2c(OC)cccc12
Structure:
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