| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-mannosidase |
|---|
| Ligand | BDBM50204663 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1627859 |
|---|
| Ki | 390000±n/a nM |
|---|
| Citation |  Olsen, JI; Plata, GB; Padrón, JM; López, Ó; Bols, M; Fernández-Bolaños, JG Selenoureido-iminosugars: A new family of multitarget drugs. Eur J Med Chem123:155-160 (2016) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-mannosidase |
|---|
| Name: | Alpha-mannosidase |
|---|
| Synonyms: | Alpha-mannosidase | Alpha-mannosidase, heavy subunit | Alpha-mannosidase, light subunit | JBM | Jbalpha-man |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 108565.93 |
|---|
| Organism: | Canavalia ensiformis |
|---|
| Description: | ChEMBL_109557 |
|---|
| Residue: | 959 |
|---|
| Sequence: | MKYNTGAGTVPEQLNVHLVPHSHDDVGWLKTVDQYYVGSENYIQEACVENVLDSVVMSLQ
RDPNRKFVFGEMAFFHRWWLEQTPETKELKLVKAGQLEFVNGGWCMHDEATTHYIDMIDH
TTLGHRFLQEQFNKIPRAGWQIDPFGHSAVQGYLLGAELGFDSVHFARIDYQDREKRKGE
KSLEVVWRGSKTFGSSAQIFANAFPGHYGPPNGFNFEVRNNFVPLQDDPRLFDTNVEERV
QNFLDAALTQAKLTRTNHLMWTMGDDFQYQYAESWFKQMDKLLHHVNKDGRVNALYSTPS
LYTEAKNAANQTWPLKIDDYFPYADGRNAYWTGFYTSRMLSGYYLATRHSGFFAGKKSTK
YHAFDLADALGIAQHHDAVSGTAKQHTTNDYAKRLALGASKAEAVVSSSLACLTSKQSAD
QCSAPASAFSQCHLFNISYCPPTESSLPDDKSLVVVVYNPLGWSRNEIVRIPVNDANLVV
KDSSGNKLEVQYVEMDDVTANLRSFYVKYWSLFKASVPPLGWSTYFISEATGKGTRNALT
LSQKGETLNIGPGDLKMSFSSLTGQLKRMYNSKTGVDLPIQQNYLWYESSEGDFSDYQAS
GAYLFRPNGQPPPHTVSRSSVTRVTRGPLVDEVHQKFNSWISQVTRLYKDKDHAEIEFTI
GPIPTDDGVGKEVITRMTSTMATNKEFYTDSNGRDFLKRVRDYREDWPLEVTQPVAGNYY
PLNLGLYTKDEKSEFSVLVDRATGGASIKDGEVELMLHRRTLRDDGRGVGEPLDEQVCMN
KEYTCEGLTVRGNYYLSIHKPAGGSRWRRTTGQEIYSPMLLAFTQENMENWKSSHSTKAY
AMDPNYSLPPSVALITLEELDDGLVLLRLAHLYEPSEDAEYSTLTKVELKKLFATQKLEE
LREVSLSANQEKSEMKKMKWSVEGDNEQEPQAVRGGPVSNADFVVELGPMEIRTFLLQF
|
|
|
|---|
| BDBM50204663 |
|---|
| Name | BDBM50204663 |
|---|
| Synonyms: | CHEMBL3894489 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H28BrN3O4Se |
|---|
| Mol. Mass. | 509.3 |
|---|
| SMILES | OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1CCCCCNC(=[Se])Nc1ccc(Br)cc1 |r| |
|---|
| Structure | 
|
|---|
| n/a |
|---|
Search and Browse
