Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetNeurotensin receptor
LigandBDBM50048908
Substrate/Competitorn/a
Meas. Tech.ChEBML_1629221
Ki 1.2±n/a nM
Citation Simeth, NABause, MDobmeier, MKling, RCLachmann, DHübner, HEinsiedel, JGmeiner, PKönig, B NTS2-selective neurotensin mimetics with tetrahydrofuran amino acids. Bioorg Med Chem25:350-359 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Neurotensin receptor
Name:Neurotensin receptor
Synonyms:Levocabastine-sensitive neurotensin receptor | NT-R-2 | NTR2 | NTR2 receptor | Neurotensin receptor 2 | Neurotensin receptor type 2
Type:PROTEIN
Mol. Mass.:45404.76
Organism:Homo sapiens (Human)
Description:ChEMBL_1281495
Residue:410
Sequence:
METSSPRPPRPSSNPGLSLDARLGVDTRLWAKVLFTALYALIWALGAAGNALSAHVVLKA
RAGRAGRLRHHVLSLALAGLLLLLVGVPVELYSFVWFHYPWVFGDLGCRGYYFVHELCAY
ATVLSVAGLSAERCLAVCQPLRARSLLTPRRTRWLVALSWAASLGLALPMAVIMGQKHEL
ETADGEPEPASRVCTVLVSRTALQVFIQVNVLVSFVLPLALTAFLNGVTVSHLLALCSQV
PSTSTPGSSTPSRLELLSEEGLLSFIVWKKTFIQGGQVSLVRHKDVRRIRSLQRSVQVLR
AIVVMYVICWLPYHARRLMYCYVPDDAWTDPLYNFYHYFYMVTNTLFYVSSAVTPLLYNA
VSSSFRKLFLEAVSSLCGEHHPMKRLPPKPQSPTLMDTASGFGDPPETRT
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50048908
NameBDBM50048908
Synonyms:CHEMBL415788
TypeSmall organic molecule
Emp. Form.C38H64N12O8
Mol. Mass.816.9904
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a