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Target
Pancreatic triacylglycerol lipase
Ligand
BDBM50207373
Substrate
n/a
Meas. Tech.
ChEBML_1631102
IC50
15480±n/a nM
Citation
 Sridhar, SN; Ginson, G; Venkataramana Reddy, PO; Tantak, MP; Kumar, D; Paul, AT Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors. Bioorg Med Chem 25:609-620 (2017) [PubMed]  Article 
Target
Name:
Pancreatic triacylglycerol lipase
Synonyms:
LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase
Type:
Enzyme
Mol. Mass.:
50080.69
Organism:
Sus scrofa (Pig)
Description:
P00591
Residue:
450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQKNILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPCPSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASKITVERNDGKVYDFCSQETVREEVLLTLNPC
  
Inhibitor
Name:
BDBM50207373
Synonyms:
CHEMBL3931385
Type:
Small organic molecule
Emp. Form.:
C25H19N3O2
Mol. Mass.:
393.4373
SMILES:
CCn1c2ccccc2c2cc(ccc12)C(=O)C(=O)Nc1ccc2ncccc2c1
Structure:
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