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Target
Substance-K receptor
Ligand
BDBM50212987
Substrate
n/a
Meas. Tech.
ChEMBL_209380 (CHEMBL857872)
Ki
0.100000±n/a nM
Citation
  TBA Bioorg Med Chem Lett 4:1951-1956 (1994)   
Target
Name:
Substance-K receptor
Synonyms:
NK-2 receptor | NK-2R | NK2R_RAT | Neurokinin 2 receptor | Neurokinin A receptor | Neurokinin NK2 | SKR | Substance-K receptor | Tac2r | Tachykinin receptor 2 | Tacr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43868.63
Organism:
Rattus norvegicus (Rat)
Description:
Neurokinin NK2 TACR2 Murine::P16610
Residue:
390
Sequence:
MGTRAIVSDANILSGLESNATGVTAFSMPGWQLALWATAYLALVLVAVTGNATVIWIILAHERMRTVTNYFIINLALADLCMAAFNATFNFIYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAIIAGIWLVALALASPQCFYSTITVDEGATKCVVAWPNDNGGKMLLLYHLVVFVLIYFLPLLVMFGAYSVIGLTLWKRAVPRHQAHGANLRHLQAKKKFVKAMVLVVLTFAICWLPYHLYFILGTFQEDIYYHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTHTPSLSRRVNRCHTKETLFMTGDMTHSEATNGQVGSPQDGEPAGPICKAQA
  
Inhibitor
Name:
BDBM50212987
Synonyms:
CHEMBL2110370 | GR-159897
Type:
Small organic molecule
Emp. Form.:
C23H27FN2O2S
Mol. Mass.:
414.536
SMILES:
COC1(C[S@@+]([O-])c2ccccc2)CCN(CCc2c[nH]c3ccc(F)cc23)CC1 |r|
Structure:
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