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TargetAdenosine receptor A1/Alpha-2A adrenergic receptor
LigandBDBM50213348
Substrate/Competitorn/a
Meas. Tech.ChEMBL_33194
EC50 2.3±n/a nM
Citation  Pharmacological evaluation of UK-14,304 analogs at cloned human adrenergic receptors Bioorg Med Chem Lett5:2255-2258 (1995)  
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1/Alpha-2A adrenergic receptor
Name:Adenosine receptor A1/Alpha-2A adrenergic receptor
Synonyms:Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens]
Type:Enzyme
Mol. Mass.:48979.91
Organism:Homo sapiens (Human)
Description:P08913
Residue:450
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGG
PQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA
APPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSD
HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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  Blast E-value cutoff:
BDBM50213348
NameBDBM50213348
Synonyms:CHEMBL72753
TypeSmall organic molecule
Emp. Form.C11H10ClN5
Mol. Mass.247.684
SMILESClc1c(NC2=NCCN2)ccc2nccnc12 |t:4|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a