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TargetD(3) dopamine receptor
LigandBDBM50216344
Substrate/Competitorn/a
Meas. Tech.ChEMBL_62588
Ki 2.0±n/a nM
Citation Avenell, KYBoyfield, IColdwell, MCHadley, MSHealy, MAJeffrey, PMJohnson, CNNash, DJRiley, GJScott, EESmith, SAStacey, RStemp, GThewlis, KM Fused aminotetralins: novel antagonists with high selectivity for the dopamine D3 receptor. Bioorg Med Chem Lett8:2859-64 (1998) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
D(3) dopamine receptor
Name:D(3) dopamine receptor
Synonyms:D2-like dopamine receptor | DOPAMINE D3 | DRD3 | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:n/a
Mol. Mass.:44243.43
Organism:Homo sapiens (Human)
Description:n/a
Residue:400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50216344
NameBDBM50216344
Synonyms:CHEMBL319116
TypeSmall organic molecule
Emp. Form.C29H32N2O2
Mol. Mass.440.5766
SMILES[H][C@]12CCc3c(O)cccc3[C@]1([H])CCN2CCCCNC(=O)c1ccc(cc1)-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a