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Target
cAMP-dependent protein kinase catalytic subunit gamma
Ligand
BDBM50011236
Substrate
n/a
Meas. Tech.
ChEMBL_161403 (CHEMBL768312)
IC50
2000±n/a nM
Citation
 Ricouart, A; Gesquiere, JC; Tartar, A; Sergheraert, C Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem 34:73-8 (1991) [PubMed]  Article 
Target
Name:
cAMP-dependent protein kinase catalytic subunit gamma
Synonyms:
KAPCG_HUMAN | PKA C-gamma | PRKACG | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic subunit gamma
Type:
PROTEIN
Mol. Mass.:
40442.03
Organism:
Homo sapiens (Human)
Description:
ChEMBL_104720
Residue:
351
Sequence:
MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
  
Inhibitor
Name:
BDBM50011236
Synonyms:
CHEMBL344314 | Isoquinoline-5-sulfonic acid (2-amino-ethyl)-amide | Isoquinolinesulfonamide, H-9 | N-(2-aminoethyl)isoquinoline-5-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C11H13N3O2S
Mol. Mass.:
251.305
SMILES:
NCCNS(=O)(=O)c1cccc2cnccc12
Structure:
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