Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50006677
Substrate
n/a
Meas. Tech.
ChEMBL_39798 (CHEMBL876771)
IC50
2200±n/a nM
Citation
 Cushman, M; Nagarathnam, D; Gopal, D; Chakraborti, AK; Lin, CM; Hamel, E Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization. J Med Chem 34:2579-88 (1991) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50006677
Synonyms:
1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl]-benzene | 1,2,3-Trimethoxy-5-[2-(4-methoxy-phenyl)-vinyl]-benzene | 10Z-3,4,4',5-tetramethoxystilbene | 3,4,4',5-tetramethoxy-(Z)-stilbene | 5-(4-methoxystyryl)-1,2,3-trimethoxybenzene | CHEMBL47426 | Trans-1,2,3-Trimethoxy-5-[2-(4-methoxyphenyl)-vinyl]-benzene (13)
Type:
Small organic molecule
Emp. Form.:
C18H20O4
Mol. Mass.:
300.349
SMILES:
COc1ccc(\C=C/c2cc(OC)c(OC)c(OC)c2)cc1
Structure:
Search PDB for entries with ligand similarity: