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TargetMelatonin receptor
LigandBDBM50230951
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1645057
Ki 2.0±n/a nM
Citation Landagaray, EEttaoussi, MRami, MBoutin, JACaignard, DHDelagrange, PMelnyk, PBerthelot, PYous, S New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation. Eur J Med Chem127:621-631 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50230951
NameBDBM50230951
Synonyms:CHEMBL4095210
TypeSmall organic molecule
Emp. Form.C14H17N3OS
Mol. Mass.275.369
SMILESCNC(=S)NCCc1cccc2ccc(OC)nc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a