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Target
Melatonin receptor type 1B
Ligand
BDBM50230964
Substrate
n/a
Meas. Tech.
ChEMBL_1645058 (CHEMBL3993987)
Ki
6.0±n/a nM
Citation
 Landagaray, E; Ettaoussi, M; Rami, M; Boutin, JA; Caignard, DH; Delagrange, P; Melnyk, P; Berthelot, P; Yous, S New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation. Eur J Med Chem 127:621-631 (2017) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50230964
Synonyms:
CHEMBL4097693
Type:
Small organic molecule
Emp. Form.:
C14H15FN2O2
Mol. Mass.:
262.2795
SMILES:
COc1cnc2cccc(CCNC(=O)CF)c2c1
Structure:
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