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TargetBeta-2 adrenergic receptor and beta-3 adrenergic receptor
LigandBDBM27960
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1648530
Kd 0.245471±n/a nM
Citation Schmidt, DGunera, JBaker, JGKolb, P Similarity- and Substructure-Based Development of฿ ACS Med Chem Lett8:481-485 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Name:Beta-2 adrenergic receptor and beta-3 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | B2AR | Beta-2 adrenergic receptor | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM27960
NameBDBM27960
Synonyms:(2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol | CHEMBL198059 | ICI118551
TypeSmall organic molecule
Emp. Form.C17H27NO2
Mol. Mass.277.4018
SMILESCC(C)N[C@@H](C)[C@@H](O)COc1ccc(C)c2CCCc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a