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TargetProstanoid DP receptor
LigandBDBM50233520
Substrate/Competitorn/a
Meas. Tech.ChEBML_1650983
IC50>10000±n/a nM
Citation Sandham, DABarker, LBrown, LBrown, ZBudd, DCharlton, SJChatterjee, DCox, BDubois, GDuggan, NHall, EHatto, JMaas, JManini, JProfit, RRiddy, DRitchie, CSohal, BShaw, DStringer, RSykes, DAThomas, MTurner, KLWatson, SJWest, RWillard, EWilliams, GWillis, J Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP ACS Med Chem Lett8:582-586 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostanoid DP receptor
Name:Prostanoid DP receptor
Synonyms:Prostaglandin D2 | Prostaglandin D2 receptor
Type:Enzyme
Mol. Mass.:40288.87
Organism:Homo sapiens (Human)
Description:Q13258
Residue:359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV
FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST
LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG
TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT
RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS
EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50233520
NameBDBM50233520
Synonyms:FEVIPIPRANT | Fevipiprant | NVP-QAW039 | QAW039
TypeSmall organic molecule
Emp. Form.C19H17F3N2O4S
Mol. Mass.426.409
SMILESCc1c(CC(O)=O)c2cccnc2n1Cc1ccc(cc1C(F)(F)F)S(C)(=O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a