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TargetDopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)
LigandBDBM50024211
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1660348
Ki>10000±n/a nM
Citation Glennon, RA The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The"Phenylalkylaminome" with a Focus on Selected Drugs of Abuse. J Med Chem60:2605-2628 (2017) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)
Name:Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)
Synonyms:5-HT-2 | 5-HT-2A | 5-HT-S1A | 5-HT-S2 | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | HTR2A | Serotonin Receptor 2A
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:52852.05
Organism:Rattus norvegicus (rat)
Description:Rat cortex membranes 5-HT2A receptors.
Residue:471
Sequence:
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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  Blast E-value cutoff:
BDBM50024211
NameBDBM50024211
Synonyms:(+/-)2-(3-Methoxy-phenyl)-1-methyl-ethylamine | 2-(3-Methoxy-phenyl)-1-methyl-ethylamine | 2-(3-Methoxy-phenyl)-1-methyl-ethylamine(MMA) | CHEMBL16247
TypeSmall organic molecule
Emp. Form.C10H15NO
Mol. Mass.165.2322
SMILESCOc1cccc(CC(C)N)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a