Reaction Details Report a problem with these data
Target
Alpha-fucosidase-like protein
Ligand
BDBM50065258
Substrate
n/a
Meas. Tech.
Enzyme Assay
pH
7±0
Temperature
310.15±0 K
Kd
55.1±10.1 nM
Citation
 Lammerts van Bueren, A; Popat, SD; Lin, CH; Davies, GJ Structural and thermodynamic analyses of α-L-fucosidase inhibitors. Chembiochem 11:1971-4 (2010) [PubMed]  Article 
Target
Name:
Alpha-fucosidase-like protein
Synonyms:
Alpha-fucosidase
Type:
Protein
Mol. Mass.:
49785.16
Organism:
Bacteroides thetaiotaomicron
Description:
Q8ABG8
Residue:
461
Sequence:
MKHIAFLSVKWMSVGLGMLSLLLSVASCGDKEYGDAMNEAQLMNDIEVNVGSSLPLAVGMDFVLDYKPVPENVTNPEITLTSSDENVVSVSQDGRVTAKMIGKAYINLSQSTAFETLKTIEVQVMPVATAIELENVELFEGTNKKVIVNVTPSDGYNVFDWKSDNEEVATVADDGTITGKKPGTANISVSSQDGSQLTATAVVTVKEVIPIDKITLSEPGYDMMIGDKTLINCLLEPIDASVGLLSWSTTNDRVATVDADGLVTAVGAGEAEIIAQDPLSGLSASIAVKVVGEGVVSLSLSYVRNQDELKALGWGFGQTPASVNFDAEGMTVNMSLQSNSKYRADLKMASNDRPVVLNIGTYRYLAFRMDVPGNGSLKLDTNKGDYGNNPTGVLAEDSQVIYYDLQAKPYFPTDAPSDKLTTFQLKIADVTVQPYSYKVYWVRTFKTLEDLKVYVEKENNK
  
Inhibitor
Name:
BDBM50065258
Synonyms:
(2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol | CHEMBL314772 | Fucosidase Inhibitor, 3
Type:
Small organic molecule
Emp. Form.:
C6H13NO3
Mol. Mass.:
147.1723
SMILES:
C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: