Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM85198
Substrate
n/a
Ki
728±n/a nM
Comments
PDSP_942
Citation
 Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther 283:1305-22 (1997) [PubMed] 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM85198
Synonyms:
CAS_127096 | Hydroxynefazodone | NSC_127096
Type:
Small organic molecule
Emp. Form.:
C25H32ClN5O3
Mol. Mass.:
486.006
SMILES:
CC(O)c1nn(CCCN2CCN(CC2)c2ccc(Cl)cc2)c(=O)n1CCOc1ccccc1
Structure:
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