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Target
Delta-type opioid receptor
Ligand
BDBM50128080
Substrate
n/a
Ki
1.5±n/a nM
Comments
PDSP_772
Citation
 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr 178:440-66 (1998) [PubMed] 
Target
Name:
Delta-type opioid receptor
Synonyms:
Delta opioid receptor | Delta-type opioid receptor | OPIATE Delta | OPRD1 | OPRD_PIG
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25736.90
Organism:
GUINEA PIG
Description:
OPIATE Delta OPRD1 GUINEA PIG::P79291
Residue:
228
Sequence:
GIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILVITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
  
Inhibitor
Name:
BDBM50128080
Synonyms:
CHEMBL217379 | DYNORPHIN(1-8)-OH | Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-OH
Type:
Small organic molecule
Emp. Form.:
C46H72N14O10
Mol. Mass.:
981.1517
SMILES:
CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(O)=O
Structure:
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