Reaction Details Report a problem with these data
Target
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
Ligand
BDBM85473
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
5.8±0
Temperature
310.15±0 K
Ki
1400000±0 nM
Citation
 Risley, JM; Huang, DH; Kaylor, JJ; Malik, JJ; Xia, YQ Glycosylasparaginase inhibition studies: competitive inhibitors, transition state mimics, noncompetitive inhibitors. J Enzym Inhib 16:269-74 (2001) [PubMed]  Article 
Target
Name:
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
Synonyms:
AGA | ASPG_HUMAN | Glycosylasparaginase (GA) | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
Type:
Enzyme
Mol. Mass.:
37206.38
Organism:
Homo sapiens (Human)
Description:
P20933
Residue:
346
Sequence:
MARKSNLPVLLVPFLLCQALVRCSSPLPLVVNTWPFKNATEAAWRALASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEKNQPTEEKVDCI
  
Inhibitor
Name:
BDBM85473
Synonyms:
L-Cysteic acid, 8 | L-cysteic acid
Type:
Small organic molecule
Emp. Form.:
C3H7NO5S
Mol. Mass.:
169.156
SMILES:
NC(CS(O)(=O)=O)C(O)=O
Structure:
Search PDB for entries with ligand similarity: