Reaction Details Report a problem with these data
Target
Hrh3 protein
Ligand
BDBM22904
Substrate
n/a
Ki
1.5±n/a nM
Comments
PDSP_1585
Citation
 Lovenberg, TW; Pyati, J; Chang, H; Wilson, SJ; Erlander, MG Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles. J Pharmacol Exp Ther 293:771-8 (2000) [PubMed] 
Target
Name:
Hrh3 protein
Synonyms:
HISTAMINE H3 | HRH3 | Hrh3 protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37860.96
Organism:
RAT
Description:
Q5PPG3
Residue:
344
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
  
Inhibitor
Name:
BDBM22904
Synonyms:
(2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alpha-Methylhistamine | Alpha-Methylhistamine-R | Alpha-Methylhistane-R | CHEMBL268229 | R-alpha-methylhistamine | RAMH
Type:
Small organic molecule
Emp. Form.:
C6H11N3
Mol. Mass.:
125.1716
SMILES:
C[C@@H](N)Cc1cnc[nH]1 |r|
Structure:
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