Reaction Details Report a problem with these data
Target
Alpha-2A adrenergic receptor
Ligand
BDBM85676
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_364
Citation
 Brink, CB; Wade, SM; Neubig, RR Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s). J Pharmacol Exp Ther 294:539-47 (2000) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
Alpha-2A adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48998.96
Organism:
PIG
Description:
adrenergic Alpha2 0 PIG::P18871
Residue:
450
Sequence:
MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGGQQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAAALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSEHAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM85676
Synonyms:
BHT-933 | CAS_128-37-0 | NSC_169743
Type:
Small organic molecule
Emp. Form.:
C9H15N3O
Mol. Mass.:
181.2349
SMILES:
CCN1CCc2nc(N)oc2CC1
Structure:
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