Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM29135
Substrate
n/a
Ki
34±n/a nM
Comments
PDSP_2003
Citation
 Borowsky, B; Adham, N; Jones, KA; Raddatz, R; Artymyshyn, R; Ogozalek, KL; Durkin, MM; Lakhlani, PP; Bonini, JA; Pathirana, S; Boyle, N; Pu, X; Kouranova, E; Lichtblau, H; Ochoa, FY; Branchek, TA; Gerald, C Trace amines: identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci U S A 98:8966-71 (2001) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM29135
Synonyms:
CHEMBL11608 | cid_5610 | p-Tyramine | tyramine
Type:
Small organic molecule
Emp. Form.:
C8H11NO
Mol. Mass.:
137.179
SMILES:
NCCc1ccc(O)cc1
Structure:
Search PDB for entries with ligand similarity: