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Target
Neurotensin receptor type 2
Ligand
BDBM82078
Substrate
n/a
Ki
7±n/a nM
Comments
PDSP_1308
Citation
 Pettibone, DJ; Hess, JF; Hey, PJ; Jacobson, MA; Leviten, M; Lis, EV; Mallorga, PJ; Pascarella, DM; Snyder, MA; Williams, JB; Zeng, Z The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin. J Pharmacol Exp Ther 300:305-13 (2002) [PubMed]  Article 
Target
Name:
Neurotensin receptor type 2
Synonyms:
NTR2_MOUSE | Neurotensin 2 | Neurotensin receptor type 2 | Ntsr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46391.18
Organism:
MOUSE
Description:
P70310
Residue:
416
Sequence:
METSSLWPPRPSPSAGLSLEARLGVDTRLWAKVLFTALYSLIFALGTAGNALSVHVVLKARAGRPGRLRYHVLSLALSALLLLLISVPMELYNFVWSHYPWVFGDLGCRGYYFVRELCAYATVLSVASLSAERCLAVCQPLRARRLLTPRRTRRLLSLVWVASLGLALPMAVIMGQKHEMERADGEPEPASRVCTVLVSRATLQVFIQVNVLVSFVLPLALTAFLNGITVNHLVALYSQVPSASAQVNSIPSRLELLSEEGLLGFITWRKTLSLGVQASLVRHKDASQIRSLQHSAQVLRAIVAVYVICWLPYHARRLMYCYIPDDGWTDELYDFYHYFYMVTNTLFYVSSAVTPVLYNAVSSSFRKLFLESLSSLCGEQRSVVPLPQEAPESTTSTYSFRLWGSPRNPSLGEIQV
  
Inhibitor
Name:
BDBM82078
Synonyms:
CAS_55508-42-4 | NSC_128644 | Neurotensin
Type:
Small organic molecule
Emp. Form.:
C36H58N8O9
Mol. Mass.:
746.8939
SMILES:
CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCCN1C(=O)C(CC(N)=O)NC(=O)C(N)CCCCN)C(=O)NC(CC(C)C)C(O)=O
Structure:
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