Reaction Details Report a problem with these data
Target
Promotilin
Ligand
BDBM50127141
Substrate
n/a
Ki
1288.25±n/a nM
Comments
PDSP_6110
Citation
 Carreras, CW; Siani, MA; Santi, DV; Dillon, SB Stable expression of a synthetic gene for the human motilin receptor: use in an aequorin-based receptor activation assay. Anal Biochem 300:146-51 (2002) [PubMed]  Article 
Target
Name:
Promotilin
Synonyms:
MLN | MOTI_HUMAN | Motilin | Promotilin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12919.83
Organism:
Homo sapiens (Human)
Description:
Motilin 0 HUMAN::P12872
Residue:
115
Sequence:
MVSRKAVAALLVVHVAAMLASQTEAFVPIFTYGELQRMQEKERNKGQKKSLSVWQRSGEEGPVDPAEPIREEENEMIKLTAPLEIGMRMNSRQLEKYPATLEGLLSEMLPQHAAK
  
Inhibitor
Name:
BDBM50127141
Synonyms:
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2R,3S,4R,6S)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione | 11-(4-dimethylamino-3-hydroxy-6-methyltetrahydro-2H-2-pyranyloxy)-3-ethyl-4,5,10-trihydroxy-13-(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-2-pyranyloxy)-4,6,8,10,12,14-hexamethyl-2-oxacyclotetradecane-1,7-dione | CHEMBL532 | Eryhtromycin A | erythromycin | erythromycin-A
Type:
Small organic molecule
Emp. Form.:
C37H67NO13
Mol. Mass.:
733.9268
SMILES:
CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@H]2O[C@@H](C)C[C@H]([C@@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O |r|
Structure:
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