Reaction Details Report a problem with these data
Target
Linoleate 9S-lipoxygenase-4
Ligand
BDBM4375
Substrate
n/a
Meas. Tech.
Inhibition Assay
Temperature
298.15±0 K
IC50
600000±15000 nM
Citation
 Koukoulitsa, C; Hadjipavlou-Litina, D; Geromichalos, GD; Skaltsa, H Inhibitory effect on soybean lipoxygenase and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum. J Enzyme Inhib Med Chem 22:99-104 (2007) [PubMed]  Article 
Target
Name:
Linoleate 9S-lipoxygenase-4
Synonyms:
LOX1.5 | LOX4 | LOX4_SOYBN | Lipoxygenase
Type:
Protein
Mol. Mass.:
96526.62
Organism:
Glycine max (Soybean) (Glycine hispida)
Description:
P38417
Residue:
853
Sequence:
MFPFGQKGQKIKGTMVVMQKNVLDINSITSVGGIVDQGLGFIGSAVDALTFAATKISIQLISATKADGGKGKIGKSTNLRGKITLPTLGAGEQAYDVNFEWDSDFGIPGAFYIKNFMQNEFYLKSLILEDIPNHGTIHFVCNSWVYNSKNYKTDRIFFANNTYLPSETPAPLLKYREEELKNVRGDGTGERKEWDRIYDYDVYNDLGNPDSGDKYARPVLGGSALPYPRRERTGRGKTRKDPNSEKPSDFVYLPRDEAFGHLKSSDFLAYGIKSVSQDVLPVLTDAFDGNILSLEFDNFAEVHKLYEGGVTLPTNFLSKIAPIPVIKEIFRTDGEQFLKYPPPKVMQVDKSAWMTDEEFARETIAGLNPNVIKIIEEFPLSSKLDTQAYGDHTCIIAKEHLEPNLGGLTVEQAIQNKKLFILDHHDYLIPYLRKINANTTKTYATRTIFFLKDDGTLTPLAIELSKPHPQGEEYGPVSEVYVPASEGVEAYIWLLAKAYVVVNDACYHQIISHWLSTHAIVEPFVIATNRQLSVVHPIYKLLFPHYRDTMNINSLARKALVNADGIIEKTFLWGRYSMEMSAVIYKDWVFTDQALPNDLVKRGVAVKDPSAPHGVRLLIEDYPYASDGLEIWDAIKSWVQEYVSFYYKSDEELQKDPELQAWWKELVEVGHGDLKDKPWWQKMQTREELVEASAILIWIASALHAAVNFGQYPYGGLILNRPTISRRFMPEKGSPEYDALAKNPEKEFLKTITGKKETLIDLTVIEILSRHASDEFYLGQRDGGDYWTSDAGPLEAFKRFGKKLEEIEKKLIEKNKDETLRNRYGPAKMPYTLLYPSSEEGLTFRGIPNSISI
  
Inhibitor
Name:
BDBM4375
Synonyms:
(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid | (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid (9) | 3,4-Dihydroxycinnamate, XVII | CHEMBL145 | Caffeic acid | Caffeic acid, 1 | cid_689043
Type:
Small organic molecule
Emp. Form.:
C9H8O4
Mol. Mass.:
180.1574
SMILES:
OC(=O)\C=C\c1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: