Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM50005247
Substrate
n/a
Ki
108±n/a nM
Comments
PDSP_3076
Citation
 Setola, V; Hufeisen, SJ; Grande-Allen, KJ; Vesely, I; Glennon, RA; Blough, B; Rothman, RB; Roth, BL 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. Mol Pharmacol 63:1223-9 (2003) [PubMed]  Article 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM50005247
Synonyms:
(+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | (-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | (R)-(-)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | (S)-(+)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | 2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | 2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine((R)-(-)-MDA) | 3,4-methylenedioxyamphetamine | CHEMBL6731 | MDA | MDA, (R,S) | MDA,R(-) | Tenamfetamine | methylenedioxyamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H13NO2
Mol. Mass.:
179.2157
SMILES:
CC(N)Cc1ccc2OCOc2c1
Structure:
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