Reaction Details Report a problem with these data
Target
Cholinergic receptor nicotinic alpha 6 subunit
Ligand
BDBM86241
Substrate
n/a
Ki
502±n/a nM
Comments
PDSP_666
Citation
 Vailati, S; Moretti, M; Longhi, R; Rovati, GE; Clementi, F; Gotti, C Developmental expression of heteromeric nicotinic receptor subtypes in chick retina. Mol Pharmacol 63:1329-37 (2003) [PubMed]  Article 
Target
Name:
Cholinergic receptor nicotinic alpha 6 subunit
Synonyms:
Cholinergic, Nicotinic Alpha6Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
57281.61
Organism:
Chick
Description:
Cholinergic, Nicotinic Alpha6Beta2 0 Chick::F7CGJ7
Residue:
492
Sequence:
MLTDKCLGLFHSRLYLWAFILTLFFKGCAVCEPEERLFQKLFSHYNQFIRPVENVSDPVTVHFEVAISQLANVDEVNQIMETNLWLRHIWNDYKLRWNPGEYDGIEFVRVPADKIWKPDIVLYNNAVGDFQVEGKTKALLKYDGMINWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIVDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPRVLMMKRPLEKKVEKFSDKDSKGFARKLAKMNYGEDAKSIKERGCCQCNPSNELSSNKRRLSYHSLKWMTELLQYSSEVTDVIDSVQFIAENMRNQNETKEVEDDWKYVAMVVDRVFLWVFIIVCVFGTAGLFLQPLIGNTV
  
Inhibitor
Name:
BDBM86241
Synonyms:
CAS_23255-54-1 | Dihydro-Beta-erythroidine | NSC_31762
Type:
Small organic molecule
Emp. Form.:
C16H21NO3
Mol. Mass.:
275.3428
SMILES:
COC1CC=C2CCN3CCC4=C(CC(=O)OC4)C23C1 |t:4,11|
Structure:
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