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Target
Beta-2 adrenergic receptor
Ligand
BDBM25769
Substrate
n/a
Ki
2170±n/a nM
Comments
PDSP_1660
Citation
 Hoffmann, C; Leitz, MR; Oberdorf-Maass, S; Lohse, MJ; Klotz, KN Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 369:151-9 (2004) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM25769
Synonyms:
4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol | Levalbuterol | Proventil | Salbutamol | Salbutamol,(+/-) | albuterol
Type:
Small organic molecule
Emp. Form.:
C13H21NO3
Mol. Mass.:
239.3107
SMILES:
CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
Structure:
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