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TargetHRH3
LigandBDBM50074629
Substrate/Competitorn/a
Ki 0.25±n/a nM
CommentsPDSP_4081
Citation Esbenshade, TAFox, GBKrueger, KMMiller, TRKang, CHDenny, LIWitte, DGYao, BBPan, LWetter, JMarsh, KBennani, YLCowart, MDSullivan, JPHancock, AA Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties. J Pharmacol Exp Ther313:165-75 (2005) [PubMed]  Article
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HRH3
Name:HRH3
Synonyms:HISTAMINE H3 | Hrh3 protein
Type:Enzyme Catalytic Domain
Mol. Mass.:37860.96
Organism:RAT
Description:Q5PPG3
Residue:344
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRF
RLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
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  Blast E-value cutoff:
BDBM50074629
NameBDBM50074629
Synonyms:4-[(1R,2R)-2-(5,5-Dimethyl-hex-1-ynyl)-cyclopropyl]-1H-imidazole | CHEMBL278462 | Cipralisant
TypeSmall organic molecule
Emp. Form.C14H20N2
Mol. Mass.216.322
SMILESCC(C)(C)CCC#C[C@@H]1C[C@H]1c1cnc[nH]1
Structure
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n/a