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Target
Adenosine 3'-phospho 5'-phosphosulfate transporter 1
Ligand
BDBM86748
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_7576
Citation
 Deecher, DC; Beyer, CE; Johnston, G; Bray, J; Shah, S; Abou-Gharbia, M; Andree, TH Desvenlafaxine succinate: A new serotonin and norepinephrine reuptake inhibitor. J Pharmacol Exp Ther 318:657-65 (2006) [PubMed]  Article 
Target
Name:
Adenosine 3'-phospho 5'-phosphosulfate transporter 1
Synonyms:
Adenosine transporter | PAPS transporter 1 | PAPST1 | Putative MAPK-activating protein PM15 | Putative NF-kappa-B-activating protein 48 | S35B2_HUMAN | SLC35B2 | Solute carrier family 35 member B2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47529.84
Organism:
Homo sapiens (Human)
Description:
Q8TB61
Residue:
432
Sequence:
MDARWWAVVVLAAFPSLGAGGETPEAPPESWTQLWFFRFVVNAAGYASFMVPGYLLVQYFRRKNYLETGRGLCFPLVKACVFGNEPKASDEVPLAPRTEAAETTPMWQALKLLFCATGLQVSYLTWGVLQERVMTRSYGATATSPGERFTDSQFLVLMNRVLALIVAGLSCVLCKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMLMGKLVSRRSYEHWEYLTATLISIGVSMFLLSSGPEPRSSPATTLSGLILLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNFFSCLFTVGSLLEQGALLEGTRFMGRHSEFAAHALLLSICSACGQLFIFYTIGQFGAAVFTIIMTLRQAFAILLSCLLYGHTVTVVGGLGVAVVFAALLLRVYARGRLKQRGKKAVPVESPVQKV
  
Inhibitor
Name:
BDBM86748
Synonyms:
CAS_386750-22-7 | Desvenlafaxine | NSC_6918664 | O-Desmethylvenlafaxine | US9944618, Compound ID No. 181
Type:
Small organic molecule
Emp. Form.:
C16H25NO2
Mol. Mass.:
263.3752
SMILES:
CN(C)CC(c1ccc(O)cc1)C1(O)CCCCC1
Structure:
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