Reaction Details Report a problem with these data
Target
Tegument protein VP16
Ligand
BDBM87322
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3)
IC50
>3988±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the Steroid Receptor Coactivator 3 (SRC3; NCOA3): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16) PubChem Bioassay (2012)[AID] 
Target
Name:
Tegument protein VP16
Synonyms:
Alpha trans-inducing protein (VP16) | VP16_HHV11 | transactivating tegument protein VP16
Type:
PROTEIN
Mol. Mass.:
54325.13
Organism:
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1)
Description:
EBI_100271
Residue:
490
Sequence:
MDLLVDELFADMNADGASPPPPRPAGGPKNTPAAPPLYATGRLSQAQLMPSPPMPVPPAALFNRLLDDLGFSAGPALCTMLDTWNEDLFSALPTNADLYRECKFLSTLPSDVVEWGDAYVPERTQIDIRAHGDVAFPTLPATRDGLGLYYEALSRFFHAELRAREESYRTVLANFCSALYRYLRASVRQLHRQAHMRGRDRDLGEMLRATIADRYYRETARLARVLFLHLYLFLTREILWAAYAEQMMRPDLFDCLCCDLESWRQLAGLFQPFMFVNGALTVRGVPIEARRLRELNHIREHLNLPLVRSAATEEPGAPLTTPPTLHGNQARASGYFMVLIRAKLDSYSSFTTSPSEAVMREHAYSRARTKNNYGSTIEGLLDLPDDDAPEEAGLAAPRLSFLPAGHTRRLSTAPPTDVSLGDELHLDGEDVAMAHADALDDFDLDMLGDGDSPGPGFTPHDSAPYGALDMADFEFEQMFTDALGIDEYGG
  
Inhibitor
Name:
BDBM87322
Synonyms:
1H-benzimidazol-2-yl-[(E)-8-quinolylmethyleneamino]amine | MLS000758870 | N-(1H-Benzoimidazol-2-yl)-N'-[1-quinolin-8-yl-meth-(E)-ylidene]-hydrazine | N-[(E)-8-quinolinylmethylideneamino]-1H-benzimidazol-2-amine | N-[(E)-quinolin-8-ylmethylideneamino]-1H-benzimidazol-2-amine | SMR000440095 | cid_9629711
Type:
Small organic molecule
Emp. Form.:
C17H13N5
Mol. Mass.:
287.3186
SMILES:
C(N=Nc1nc2ccccc2[nH]1)c1cccc2cccnc12 |w:2.2|
Structure:
Search PDB for entries with ligand similarity: