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TargetZinc finger protein GLI1
LigandBDBM89425
Substrate/Competitorn/a
Meas. Tech.Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay
IC50 3110±n/a nM
Citation PubChem, PC Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay PubChem Bioassay(2012)[AID]  Article
More Info.:Get all data from this article,  Assay Method
 
Zinc finger protein GLI1
Name:Zinc finger protein GLI1
Synonyms:Gli1
Type:PROTEIN
Mol. Mass.:118575.39
Organism:Mus musculus
Description:EBI_101259
Residue:1111
Sequence:
MFNPMTPPQVNSYSEPCCLRPLHSQGVPSMGTEGLSGLPFCHQANFMSGSQGYGAARETS
SCTEGSLFPPPPPPRSSVKLTKKRALSISPLSDASLDLQTVIRTSPSSLVAFINSRCTSP
GGSYGHLSIGTMSPSLGFPPQMSHQKGTSPPYGVQPCVPHDSTRGSMMLHPQARGPRATC
QLKSELDMMVGKCPEDPLEGDMSSPNSTGIQDHLLGMLDGREDLEREEKPEPESVYETDC
RWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCSRELRPFKAQYMLVVHMRRHTG
EKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEQEGCSKAFSNASDRAKHQNRTHS
NEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAHVTKRHRGDGPLPRAQPLSTVEPKRE
REGGSGREESRLTVPESAMPQQSPGAQSSCSSDHSPAGSAANTDSGVEMAGNAGGSTEDL
SSLDEGPCVSATGLSTLRRLENLRLDQLHQLRPIGSRGLKLPSLTHAGAPVSRRLGPPVS
LDRRSSSSSSMSSAYTVSRRSSLASPFPPGTPPENGASSLPGLTPAQHYMLRARYASARG
SGTPPTAAHSLDRMGGLSVPPWRSRTEYPGYNPNAGVTRRASDPARAADHPAPARVQRFK
SLGCVHTPPSVATGRNFDPHHPTSVYSPQPPSITENVAMDTRGLQEEPEVGTSVMGNGLN
PYMDFSSTDTLGYGGPEGTAAEPYEARGPGSLPLGPGPPTNYGPGHCAQQVSYPDPTPEN
WGEFPSHAGVYPSNKAPGAAYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSE
GSPGPQPLFSHHPQLPQPQYPQSGPYPQPPHGYLSTEPRLGLNFNPSSSHSTGQLKAQLV
CNYVQSQQELLWEGRNRGGLPNQELPYQSPKFLGGSQVSQSPAKTPAAAAAAYGSGFAPA
SANHKSGSYPAPSPCHETFTVGVNRPSHRPAAPPRLLPPLSPCYGPLKVGDTNPSCGHPE
VGRLGAGPALYPPPEGQVCNALDSLDLDNTQLDFVAILDEAQGLSPPLSHEQGDSSKNTP
SPSGPPNMAVGNMSVLLGSLPGETQFLNSSA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM89425
NameBDBM89425
Synonyms:3-(benzenesulfonyl)-N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)propanamide | 3-besyl-N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)propionamide | MLS001237985 | N-(3-ethyl-4-methoxy-1,3-benzothiazol-2-ylidene)-3-(phenylsulfonyl)propanamide | SMR000806292 | cid_7153852
TypeSmall organic molecule
Emp. Form.C19H20N2O4S2
Mol. Mass.404.503
SMILESCCn1c2c(OC)cccc2sc1=NC(=O)CCS(=O)(=O)c1ccccc1 |w:13.15|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a