Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89865
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
709±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM89865
Synonyms:
MLS000538613 | N-(4-chlorobenzyl)-N-(2,6-dioxo-1-piperidinyl)-4-nitrobenzamide | N-(4-chlorobenzyl)-N-glutarimido-4-nitro-benzamide | N-[(4-chlorophenyl)methyl]-N-(2,6-dioxo-1-piperidinyl)-4-nitrobenzamide | N-[(4-chlorophenyl)methyl]-N-(2,6-dioxopiperidin-1-yl)-4-nitrobenzamide | N-[2,6-bis(oxidanylidene)piperidin-1-yl]-N-[(4-chlorophenyl)methyl]-4-nitro-benzamide | SMR000144650 | cid_2235475
Type:
Small organic molecule
Emp. Form.:
C19H16ClN3O5
Mol. Mass.:
401.8
SMILES:
[O-][N+](=O)c1ccc(cc1)C(=O)N(Cc1ccc(Cl)cc1)N1C(=O)CCCC1=O
Structure:
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