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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM30647
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM30647
Synonyms:
MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)ethanesulfonamide | N-[4-(2-thiazolo[5,4-b]pyridinyl)phenyl]ethanesulfonamide | N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl)phenyl]ethanesulfonamide | cid_16194594
Type:
Small organic molecule
Emp. Form.:
C14H13N3O2S2
Mol. Mass.:
319.402
SMILES:
CCS(=O)(=O)Nc1ccc(cc1)-c1nc2cccnc2s1
Structure:
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