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TargetSerum paraoxonase/arylesterase 1
LigandBDBM92332
Substrate/Competitorn/a
Meas. Tech.Paraoxonase Activity Assay
pH10.5±0
Temperature298.15±0 K
Ki 306000±0.0 nM
IC50 340000±0.0 nM
Citation Ekinci, DBeydemir, S Effect of some analgesics on paraoxonase-1 purified from human serum. J Enzyme Inhib Med Chem24:1034-9 (2009) [PubMed]  Article
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Serum paraoxonase/arylesterase 1
Name:Serum paraoxonase/arylesterase 1
Synonyms:A-esterase 1 | Aromatic esterase 1 | K-45 | PON 1 | Paraoxonase (PON1) | Paraoxonase (hPON1) | Paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Serum paraoxonase 1 (PON1)
Type:Enzyme
Mol. Mass.:39719.73
Organism:Homo sapiens (Human)
Description:P27169
Residue:355
Sequence:
MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
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  Blast E-value cutoff:
BDBM92332
n/a
NameBDBM92332
Synonyms:Tenoxicam
TypeSmall organic molecule
Emp. Form.C13H11N3O4S2
Mol. Mass.337.374
SMILESCN1C(C(=O)Nc2ccccn2)=C(O)c2sccc2S1(=O)=O |t:12|
Structure
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