Reaction Details Report a problem with these data
Target
Steroid C26-monooxygenase
Ligand
BDBM31773
Substrate
n/a
Meas. Tech.
Binding Assay
Kd
3.3e+2± 1e+1 nM
Citation
 Podust, LM; Ouellet, H; von Kries, JP; de Montellano, PR Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines. J Biol Chem 284:25211-9 (2009) [PubMed]  Article 
Target
Name:
Steroid C26-monooxygenase
Synonyms:
CP142_MYCTO | Cytochrome P450 142 | Cytochrome P450 142 (CYP142) | cyp142
Type:
Enzyme
Mol. Mass.:
41422.72
Organism:
Mycobacterium tuberculosis
Description:
P9WPL4
Residue:
372
Sequence:
MRANQPVFRDRNGLAAASTYQAVIDAERQPELFSNAGGIRPDQPALPMMIDMDDPAHLLRRKLVNAGFTRKRVKDKEASIAALCDTLIDAVCERGECDFVRDLAAPLPMAVIGDMLGVRPEQRDMFLRWSDDLVTFLSSHVSQEDFQITMDAFAAYNDFTRATIAARRADPTDDLVSVLVSSEVDGERLSDDELVMETLLILIGGDETTRHTLSGGTEQLLRNRDQWDLLQRDPSLLPGAIEEMLRWTAPVKNMCRVLTADTEFHGTALCAGEKMMLLFESANFDEAVFCEPEKFDVQRNPNSHLAFGFGTHFCLGNQLARLELSLMTERVLRRLPDLRLVADDSVLPLRPANFVSGLESMPVVFTPSPPLG
  
Inhibitor
Name:
BDBM31773
Synonyms:
ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pevaryl | cid_68589
Type:
Small organic molecule
Emp. Form.:
C18H15Cl3N2O
Mol. Mass.:
381.684
SMILES:
Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
Structure:
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